 | Vincent Price | | Dr. Warren Chapin |
| Judith Evelyn | | Mrs. Martha Ryerson Higgins |
| Philip Coolidge | | Oliver 'Ollie' Higgins |
| Darryl Hickman | | David Morris |
| Patricia Cutts | | Isabel Stevens Chapin |
| Pamela Lincoln | | Lucy Stevens |
| Leon Alton | | Member of Silent Movie Audience |
| William Castle | | Prologue Himself - Host |
| Gertrude Astor | | Member of Silent Movie Audience |
| Bob Gunderson | | Ryerson - Screaming Convict |
| Richard Barthelmess | | David Kinemon |
| Gail Bonney | | Member of Silent Movie Audience |
| Pat Colby | | Member of Silent Movie Audience |
| George DeNormand | | Member of Silent Movie Audience |
| Amy Fields | | Member of Silent Movie Audience |
| Dal McKennon | | Projectionist |
| Clarence Straight | | Member of Silent Movie Audience |
| Ernest Torrence | | Luke Hatburn, in clip from Tol'able David |
