 | Robin Williams | | Popeye |
| Shelley Duvall | | Olive Oyl |
| Ray Walston | | Poopdeck Pappy |
| Paul Dooley | | Wimpy |
| Paul L. Smith | | Bluto |
| Richard Libertini | | Geezil |
| Donald Moffat | | The Taxman |
| MacIntyre Dixon | | Cole Oyl |
| Roberta Maxwell | | Nana Oyl |
| Donovan Scott | | Castor Oyl |
| Allan F. Nicholls | | Rough House |
| Wesley Ivan Hurt | | Swee'pea |
| Bill Irwin | | Ham Gravy, the Old Boyfriend |
| Robert Fortier | | Bill Barnacle, the Town Drunk |
| David McCharen | | Harry Hotcash, the Gambler |
| Sharon Kinney | | Cherry, His Moll |
| Peter Bray | | Oxblood Oxheart, the Fighter |
| Linda Hunt | | Mrs. Oxheart, his Mudder |
| Geoff Hoyle | | Scoop, the Reporter |
| Wayne Robson | | Chizzelflint, the Pawnbroker |
| Larry Pisoni | | Chico, the Dishwasher |
| Carlo Pellegrini | | Swifty, the Cook |
| Susan Kingsley | | La Verne, the Waitress |
| Michael Christensen | | Splatz, the Janitor |
| Ray Cooper | | The Preacher |
| Noel Parenti | | Slick, the Milkman |
| Karen McCormick | | Rosie, the Milkmaid |
| John E. Bristol | | Bear, the Hermit |
| Julie Janney | | Mena Walfleur, a Steinette |
| Patty Katz | | Mina Walfleur, a Steinette |
| Diane Shaffer | | Mona Walfleur, a Steinette |
| Nathalie Blossom | | Blossom Walfleur, a Steinette |
| Dennis Franz | | Spike, a Tough |
| Alan Autry | | Slug, a Tough |
| Ned Dowd | | Butch, a Tough |
| Hovey Burgess | | Mort, a Tough |
| Roberto Messina | | Gozo, a Tough |
| Pietro Torrisi | | Bolo, a Tough |
| Margery Bond | | Daisy, a Housewife |
| Judy Burgess | | Petunia, a Housewife |
