 | Tom Hanks | | Jimmy Dugan |
| Geena Davis | | Dottie Hinson - Catcher |
| Lori Petty | | Kit Keller - Pitcher |
| Madonna | | Mae Mordabito - Center Fielder |
| Rosie O'Donnell | | Doris Murphy - Third Base |
| Megan Cavanagh | | Marla Hooch - Second Base |
| Tracy Reiner | | Betty Horn - Left Fielder-Pitcher |
| Bitty Schram | | Evelyn Gardner - Right Fielder |
| Ann Cusack | | Shirley Baker - Left Fielder |
| Anne Ramsay | | Helen Haley - First Base |
| Freddie Simpson | | Ellen Sue Gotlander - Shortstop-Pitcher |
| Renée Coleman | | LF / C Alice Gaspers |
| Robin Knight | | 'Beans' Babbitt - Shortstop |
| Patti Pelton | | Marbleann Wilkenson - Second Base |
| Kelli Simpkins | | Beverly Dixon - Outfielder |
| Neezer Tarleton | | Neezer Dalton - Outfielder |
| Connie Pounds-Taylor | | Connie Calhoun - Outfielder |
| Kathleen Marshall | | 'Mumbles' Brockman - Outfielder |
| Sharon Szmidt | | Vivian Ernst - Second Base |
| Pauline Brailsford | | Miss Cuthbert |
| David Strathairn | | Ira Lowenstein |
| Garry Marshall | | Walter Harvey |
| Jon Lovitz | | Ernie Capadino |
| Bill Pullman | | Bob Hinson |
| Justin Scheller | | Stilwell |
| Eddie Jones | | Dave Hooch |
| Alan Wilder | | Nelson |
| Michael Haley | | Empathetic Umpire |
| Don S. Davis | | Racine Coach Charlie |
| Janet Jones | | Racine Pitcher |
| Brenda Ferrari | | Racine Catcher |
| Téa Leoni | | Racine First Base |
| Laurel Cronin | | Maida Gillespie |
| Robert Stanton | | Western Union Man |
| Wantland L. Sandel Jr. | | Doctor |
| Joe Krowka | | Heckler |
| Harry Shearer | | Newsreel Announcer |
| Blaire Baron | | Margaret |
| Ryan Howell | | Jeffrey |
| Brian Boru Gleeson | | Bobby |
