 | Jason Sudeikis | | Red |
| Josh Gad | | Chuck |
| Danny McBride | | Bomb |
| Maya Rudolph | | Matilda |
| Bill Hader | | Leonard |
| Peter Dinklage | | Mighty Eagle |
| Sean Penn | | Terence |
| Keegan-Michael Key | | Judge Peckinpah |
| Kate McKinnon | | Stella |
| Tony Hale | | Ross |
| Hannibal Buress | | Edward the Birthday Dad |
| Ike Barinholtz | | Tiny |
| Tituss Burgess | | Photog |
| Ian Hecox | | Bubbles |
| Anthony Padilla | | Hal |
| Jillian Bell | | Helene the Lunch Mom / Yoga Instructor (voice) |
| Billy Eichner | | Chef Pig / Phillip (voice) |
| Danielle Brooks | | Olive Blue / Monica the Crossing Guard (voice) |
| Blake Shelton | | Earl Pig (voice) |
| Charli XCX | | Willow (voice) |
| Romeo Santos | | Early Bird (voice) |
| Cristela Alonzo | | Shirley the Old Lady Bird (voice) |
| Adam Brown | | Hug Trader (voice) |
| Ava Acres | | Timothy the Birthday Boy (voice) |
| Geoffrey Arend | | Day Care Teacher (voice) |
| Malena Brewer | | Arianna Bird (voice) |
| Catherine Winder | | Billy the Sign (voice) |
| Alex Borstein | | Sophie Bird / Peggy Bird (voice) |
| John Cohen | | Johnny Bird (voice) |
| Max Charles | | Bobby Bird (voice) |
| Clay Kaytis | | Clayton the Waiter Bird (voice) |
| Matthew J. McCarthy | | Rodney Pig / Acrobat Pig (voice) |
| Vincent Oswald | | Dylan Hatchling (voice) |
| Fergal Reilly | | Foreman Pig (voice) |
| Samantha Cohen | | Samantha Hatchling (voice) |
| Kevin Bigley | | Greg Blue (voice) |
| Maddie Taylor | | Hamilton Pig / Acrobat Pig (voice) |
| Josh Robert Thompson | | Brad Bird / Dane the Saxophone Bird (voice) |
| Ali Wong | | Betty Bird (voice) |
| Mckenna Grace | | Ella Bird (voice) |
